Inflammation and Stem Cells in Diabetic and Chronic Kidney Disease
NCT03325322 · Status: SUSPENDED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2026-01-28
Summary
The proposed studies will examine the effect of fisetin on adipose tissue-derived mesenchymal stem/stromal cell function, kidney function, markers of inflammation, and physical function in individuals with advanced chronic kidney disease.
Conditions
- Chronic Kidney Diseases
- Diabetes Mellitus
- Diabetic Nephropathies
Interventions
- DIETARY_SUPPLEMENT
-
Fisetin
Flavonoid family
- DRUG
-
Placebo oral capsule
Placebo
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
LaTonya J Hickson, MD · Mayo Clinic
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 40 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-01-02
- Primary Completion
- 2027-01-31
- Completion
- 2027-01-31
- FDA Drug
- Yes
Countries
- United States
Study Locations
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