Impact of Rifaximin Therapy on Intestinal Byproducts in End-Stage Renal Disease
NCT02738905 · Status: WITHDRAWN · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL
Last updated 2019-02-28
Summary
The purpose of this study is to determine if rifaximin reduces serum trimethylamine-N-oxide (TMAO) levels in patients with end-stage renal disease.
Conditions
Interventions
- DRUG
-
Rifaximin
One 550 mg tablet taken orally two times a day.
Sponsors & Collaborators
- collaborator OTHER
-
Jason Stubbs, MD
lead OTHER
Principal Investigators
-
Jason Stubbs, MD · University of Kansas Medical Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-01-31
- Primary Completion
- 2019-02-26
- Completion
- 2019-02-26
Countries
- United States
Study Locations
More Related Trials
-
A Study of Erythromycin and Rivaroxaban in Study Participants With Normal and Reduced Kidney Function
NCT01309438 ·Status: COMPLETED ·Phase: PHASE1
-
Dose-finding of Rivaroxaban in Hemodialysis
NCT02047006 ·Status: COMPLETED ·Phase: PHASE4
-
Pilot Study of Rituximab to Treat Fibrillary Glomerulonephritis
NCT02197767 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of RAY1225 in Participants With Impaired Kidney Function
NCT06613763 ·Status: COMPLETED ·Phase: PHASE1
-
Pilot Study of Safety, Tolerability, Pharmacokinetics/Pharmacodynamics of RP103 Compared to Cystagon® in Patients With Cystinosis
NCT00872729 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Safety of Single Doses of Peginesatide in Patients With Chronic Kidney Disease
NCT00109291 ·Status: TERMINATED ·Phase: PHASE2
-
Peginesatide for Anemia in Chronic Hemodialysis Patients
NCT00228449 ·Status: COMPLETED ·Phase: PHASE2
-
Study Assessing PK and Safety of MGTA-145 in Subjects With Normal Estimated GFR and Varying Degrees of Renal Impairment
NCT04154670 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Learn How the Body Processes the Study Medicine PF-07328948 in People With Reduced Kidney Function
NCT07315360 ·Status: RECRUITING ·Phase: PHASE1
-
A Phase 1 Study to Assess the Effect of Severe Renal Impairment on the Pharmacokinetics, as Well as Safety/Tolerability, of Ranolazine
NCT01675973 ·Status: TERMINATED ·Phase: PHASE1
-
A Study to Evaluate the Effects of Renal Impairment on the Pharmacokinetics of ELX-02
NCT03776539 ·Status: COMPLETED ·Phase: PHASE1
-
A Two-Part Phase 2a Study of RVX000222 in Patients With End-Stage Renal Disease Treated With Hemodialysis
NCT03160430 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
Effect of Febuxostat on Endothelial Dysfunction in Hemodialysis Patients.
NCT02866214 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
A Phase 1 Study of Roxadustat in Subjects With Different Degrees of Renal Function
NCT02965040 ·Status: COMPLETED ·Phase: PHASE1
-
Pentoxifylline and Progression of Chronic Kidney Disease in Moderate-to-high Risk Patients
NCT00285298 ·Status: COMPLETED ·Phase: PHASE3
-
Pharmacokinetics, Safety, and Tolerability of Methylnaltrexone (MNTX) in Subjects With Impaired Renal Function
NCT01367509 ·Status: COMPLETED ·Phase: PHASE1
-
A Renal Impairment Study for PF-04965842
NCT03660241 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Efficacy of Apixaban in Severe Renal Impairment
NCT03399305 ·Status: WITHDRAWN
-
A Study to Learn How Renal Impairment Affects the Pharmacokinetics of PF-07817883.
NCT06586216 ·Status: COMPLETED ·Phase: PHASE1
-
RBT-1 Phase 1b Clinical Trial in Healthy Volunteers and Subjects With CKD
NCT03630029 ·Status: WITHDRAWN ·Phase: PHASE1
-
Renal Impairment Study of PF-07321332 Boosted With Ritonavir in Adult Participants With Renal Impairment and in Healthy Participants With Normal Renal Function.
NCT04909853 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Efficacy Study of the Effect of Etanercept in Hemodialysis Patients
NCT00293202 ·Status: TERMINATED ·Phase: PHASE2
-
A Study to Assess Pharmacokinetic, Pharmacodynamic, Safety and Tolerability of ASKP1240 in de Novo Kidney Transplantation
NCT01279538 ·Status: COMPLETED ·Phase: PHASE1
-
Effect of Short Term Aliskiren Treatment in Kidney Transplant Patients
NCT01437943 ·Status: TERMINATED ·Phase: PHASE4
-
A Study to Evaluate the Blood Levels, Safety, and Tolerability of PF-00734200 in Subjects With Impaired Kidney Function and Normal Kidney Function
NCT00596518 ·Status: COMPLETED ·Phase: PHASE1