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Effects of Positive End-expiratory Pressure on Intracranial Pressure in Patients With Severe Traumatic Brain Injury

NCT03296293 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 38

Last updated 2017-10-02

No results posted yet for this study

Summary

The impact of PEEP on ICP was dependent on the difference between elevated CVP levels and baseline ICP levels. ICP would increase once elevated CVP through PEEP adjustment exceeds the baseline ICP.

Conditions

Interventions

OTHER

PEEP at 5cmH2O

Effect of PEEP at 5cmH2O on ICP

OTHER

PEEP at 10cmH2O

Effect of PEEP at 10cmH2O on ICP

OTHER

PEEP at 15cmH2O

Effect of PEEP at 15cmH2O on ICP

Sponsors & Collaborators

  • Hongpeng Li

    lead OTHER

Principal Investigators

  • Hongpeng Li, master · Department of Emergency and Critical Care Medicine, Zhoupu Hospital affiliated with Shanghai University of Medicine and Health Sciences, Shanghai 201318, PR China

Study Design

Allocation
NON_RANDOMIZED
Purpose
OTHER
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-08-01
Primary Completion
2017-06-15
Completion
2017-08-01

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03296293 on ClinicalTrials.gov