MedTrace Logo

An Intervention on Healthy Adults of Probiotics on Gut Flora Metabolisms of Choline

NCT03292978 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2019-11-13

No results posted yet for this study

Summary

The aim of the study is to examine the effects of probiotics intervention on choline metabolites and intestinal microbiota composition using a randomized double blind clinical trial. Also, we proposed to explore the real-time change of choline metabolites after probiotics intervention through a PC challenge test. Our study will clarify the biochemical pathway involved in metabolic diseases and hope to provide a new targeted-preventive and therapeutic strategy for chronic metabolic diseases.

Conditions

  • Healthy

Interventions

DIETARY_SUPPLEMENT

probiotics intervention

The probiotics intention is provided with 4 strains of probiotics as a 2g sachet powder, dried with corn starch for 4 weeks.

DIETARY_SUPPLEMENT

non-probiotic control

The placebo is corn starch alone provided and the shape, color, flavor and taste are same with the powder of probiotics intervention.

Sponsors & Collaborators

  • Huilian Zhu

    lead OTHER

Principal Investigators

  • Zhu Hui lian, Professor · Sun Yat-sen University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
30 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-07-01
Primary Completion
2017-12-31
Completion
2018-12-31

Countries

  • China

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03292978 on ClinicalTrials.gov