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Effect of Alfacalcidol to Respiratory Infection and Immune Response of Indonesian Elderly

NCT03292744 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 110

Last updated 2017-09-26

No results posted yet for this study

Summary

Vitamin D has been known to influence immune response through Vitamin D Receptor in Immune Cells, but only few has been known about the effect alfacalcidol, a vitamin D analog to immune system. In elderly, immune disregulation or immunosenecence have great impact to infection response. This study is aimed to determine the effect of alfacalcidol supplementation in vitro and in vivo to respiratory infection incidence and inflammatory markers, as well as T cell lymphocyte subset in Indonesian elderly patients.

Conditions

  • Frail Elderly Syndrome
  • Elderly Infection

Interventions

DRUG

Alfacalcidol

alfacalcidol 0,5 mcg

Sponsors & Collaborators

  • Indonesia University

    lead OTHER

Principal Investigators

  • Aulia Rizka, MD · Universitas Indonesia / Cipto Mangunkusumo Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-01-10
Primary Completion
2017-10-10
Completion
2017-12-15

Countries

  • Indonesia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03292744 on ClinicalTrials.gov