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Effects of DHA on Post-operative Fibrosis of Trabulectomy Blebs in Glaucoma Surgery

NCT03289806 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 20

Last updated 2017-09-21

No results posted yet for this study

Summary

Post-operative fibrosis of trabulectomy blebs is a major cause of surgical failure leading to a renewed increase in intraocular pressure. The use of anti-metabolites over many years has made it possible to improve success rates for this surgery but these drugs have numerous adverse effects as they are toxic. Alternative therapies are thus necessary, and we believe that DHA could have antifibrotic effects on fibroblasts and could thus improve success rates in this surgery.

Conditions

  • Trabulectomy
  • Deep Sclerectomy

Interventions

PROCEDURE

Samples of fibroblasts from Tenon's capsule

Sponsors & Collaborators

  • Centre Hospitalier Universitaire Dijon

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-01-12
Primary Completion
2018-01-31
Completion
2018-01-31

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03289806 on ClinicalTrials.gov