Tailoring Mobile Health Technology to Reduce Obesity and Improve Cardiovascular Health in Resource-Limited Neighborhood Environments

Summary

Background:

Heart disease is a leading cause of death. People can reduce their heart disease risk by exercising more. Mobile health technology may make people more successful at increasing their exercise. This includes things like physical activity monitors and smartphone apps.

Objective:

To find out if mobile health technology can increase physical activity.

Eligibility:

African American women ages 21-75 who:

* Are overweight or obese
* Live in certain areas near Washington, DC
* Have a smartphone that can use the study app

Design:

At visit 1, participants will

* Answer survey questions. These may be about medical history, physical activity, and weight. They may also cover body image, health perception, and spirituality.
* Have body size measured and get blood tests
* Get a device to wear on the wrist. It will record physical activity and hours of sleep.
* Learn how to download and use the study mobile app

For 2 weeks, researchers will collect data about participants physical activity.

Then participants will have a study visit with additional blood tests.

All participants will get messages from the app that encourage exercise.

Some participants will get data from the app about exercise near their home or work.

Some participants may get face-to-face coaching.

Participants may get wireless devices. These measure body weight, blood pressure, and blood glucose. Participants can measure these at home and upload the data to the app for the study.

Participants will have visits after 3 and 6 months. They will repeat the visit 1 tests.

...

Conditions

• Obesity

Interventions

DEVICE

Step it Up mobile app

Step it Up mobile app

DEVICE

Global Positioning System (GPS) Device

Global Positioning System (GPS) Device

DEVICE

Bluetooth-enabled scale

Bluetooth-enabled scale

DEVICE

Bluetooth-enabled glucometer

Bluetooth-enabled glucometer

DEVICE

MRI: Image Reconstruction and Analysis Software (Device Manufacturer: NIH)

Image Reconstruction and Analysis Software

DEVICE

MRI: Research pulse sequences (Device Manufacturer: NIH)

pulse sequences

DEVICE

MRI: radiofrequency coils (Device Manufacturer: Siemens Medical Solutions USA, Inc.)

radiofrequency coils

DEVICE

AMRA Researcher Image reconstruction software

Image reconstruction software

Sponsors & Collaborators

• George Washington University

  collaborator OTHER

• National Heart, Lung, and Blood Institute (NHLBI)

  lead NIH

Principal Investigators

• Tiffany M Powell-Wiley, M.D. · National Heart, Lung, and Blood Institute (NHLBI)

Study Design

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

SINGLE

Model

SEQUENTIAL

Eligibility

Min Age

21 Years

Max Age

75 Years

Sex

FEMALE

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2018-06-21

Primary Completion

2026-08-04

Completion

2026-08-04

Countries

• United States

Study Locations