The Impact of Air Filtration on Asthmatic Children

Summary

This study uses a crossover study design to examine the impact of a two-week bedroom based indoor air filtration on the concentration of indoor airborne pollutants, personal exposure to airborne pollutants and health indicators among asthmatic children living in Shanghai, China

Conditions

• Asthma in Children

Interventions

DEVICE

Bedroom air filtered by an air filtration device to remove airborne pollutants

The air in the bedroom of study subjects in the active comparator arm was processed by an air filtration device which pulled air through a pre-filter, a high efficiency particular air (HEPA) filter and an active carbon filter continuously. The air in the bedroom of subjects in the placebo arm was processed by a placebo air filtration device that looked identical to the real air filtration device but did not possess the HEPA filter and the active carbon filter. Each subject was assigned to the active comparator arm and the placebo arm in a randomized order with a two-week washout period scheduled in-between. The subjects, their guardians and the study staff that assessed the health indicators of the subjects were blinded to this order till the end of the study.

Sponsors & Collaborators

• Underwriters Laboratory, Inc

  collaborator UNKNOWN

• Duke University

  collaborator OTHER

• Tsinghua University

  collaborator OTHER

• University of Wisconsin, Madison

  collaborator OTHER

• Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

  lead OTHER

Principal Investigators

• Michael H. Bergin, PhD · Duke University

• Junfeng Zhang, PhD · Duke University

• James J. Schauer, PhD · University of Wisconsin, Madison

• Yinping Zhang, PhD · Tsinghua University

• Feng Li, MD · Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

TRIPLE

Model

CROSSOVER

Eligibility

Min Age

5 Years

Max Age

14 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2017-01-17

Primary Completion

2017-04-22

Completion

2020-12-31

Countries

• China

Study Locations