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Impact of Sleep Duration on Immune Balance in Urban Children With Asthma

NCT05420766 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 204

Last updated 2025-09-22

No results posted yet for this study

Summary

Urban children with asthma are at high risk for short sleep, due to an environment that jeopardizes both sleep and asthma management. Further, urban children with asthma suffer from altered immune balance, a key biological process contributing to individual differences in asthma morbidity and sleep health. In the proposed research, the researchers will examine the effects of shortened and recovery sleep on immune balance and associated changes in lung function in urban children with allergic asthma through an experimental design.

Conditions

  • Asthma in Children
  • Sleep Hygiene
  • Sleep, Inadequate

Interventions

BEHAVIORAL

Shortened Sleep

In this experimental condition, children go to bed 90 minutes later than their typical bedtime during Week 2 of the 4-week protocol.

BEHAVIORAL

Stabilized sleep

In this control condition, children go to bed at their usual time throughout the 4-week protocol.

Sponsors & Collaborators

  • Brown University

    collaborator OTHER

  • University of Mississippi Medical Center

    collaborator OTHER

  • Rhode Island Hospital

    lead OTHER

Principal Investigators

  • Daphne Koinis-Mitchell, PhD · Rhode Island Hospital

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
7 Years
Max Age
11 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-05-15
Primary Completion
2026-07-01
Completion
2026-07-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05420766 on ClinicalTrials.gov