Pollution Intervention to Impact Kids Asthma Study

Summary

The goal of this clinical trial is to learn if adding Air Quality Index (AQI) information to asthma action plans works to improve asthma outcomes in children. It will also learn about children with asthma who report being more sensitive to outdoor air pollution. The main questions it aims to answer are:

* Does adding either information about the EPA-AQI or commercial AQI improve asthma outcomes over time?
* Are there changes in nasal gene expression in children with asthma who report they are more sensitive to outdoor air pollution?

Researchers will compare EPA-AQI and the commercial-AQI groups to a control group to either AQI works to improve asthma.

Participants will:

* Receive standardized outdoor air pollution education and an asthma action plan
* Provide nose and blood specimens
* Have visits every 4 weeks for 48 weeks, 10 will be conducted by telephone calls and 3 visits will be in person.

Conditions

• Childhood Asthma
• Asthma Control
• Asthma Exacerbation
• Air Pollution, Risk Reduction Behaviors

Interventions

BEHAVIORAL

EPA-AQI

The EPA-AQI group will receive standardized outdoor air pollution education, standardized AQI education, instructions for AQI usage, and an asthma action plan containing information specific for the EPA-AQI, and will demonstrate the ability to navigate to the EPA-AQI via smartphone app or website.

BEHAVIORAL

Commerical-AQI

The commercial-AQI group will receive standardized AQI education, instructions for commercial-AQI usage, and an asthma action plan containing information specific for the commercial-AQI, and will demonstrate the ability to navigate to the commercial-AQI via smartphone or website.

BEHAVIORAL

Education and plan

Standardized outdoor air pollution education and standard asthma action plan

Sponsors & Collaborators

• National Institute of Environmental Health Sciences (NIEHS)

  collaborator NIH

• University of Pittsburgh

  lead OTHER

Principal Investigators

• Franziska Rosser, MD MPH · University of Pittsburgh

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

8 Years

Max Age

17 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2026-02-24

Primary Completion

2030-01-31

Completion

2030-01-31

Countries

• United States

Study Locations