Metabolic Effects of Differential Organ Growth Rates
NCT03219229 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 49
Last updated 2017-07-18
Summary
Young children have a high resting energy expenditure (REE) relative to their body weight and metabolically active compartment, fat-free mass (FFM). Both body weight and FFM are, however, metabolically heterogeneous and include organs and tissues varying widely in specific metabolic rate (i.e., organ REE/kg/d). One prevailing hypothesis is that most, if not all, of the higher REE observed in young animals and children compared to adults can be accounted for by a larger proportion of high metabolic rate components such as brain, liver, and heart..
Conditions
- Resting Energy Expenditure
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Dympna Gallagher · Columbia University
Eligibility
- Min Age
- 7 Years
- Max Age
- 11 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2004-02-14
- Primary Completion
- 2007-02-20
- Completion
- 2007-02-20
Countries
- United States
Study Locations
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