Breakfast and Muscle Health in Children

Summary

One in every three children ages 2-19 years is overweight or obese. Although multifactorial in nature, obesity is primarily attributed to a mismatch between energy intake and energy expenditure (EE). Daily EE (DEE) can be partitioned between resting metabolic rate (RMR), EE associated with physical activity, and the thermic effect of food (TEF). RMR corresponds to the energy needed to sustain the body functions at rest and is also related to body composition (i.e., ratio of skeletal muscle mass to fat mass). Skeletal muscle mass is a large contributor to RMR; the more skeletal muscle mass, the higher the RMR (i.e., more energy expended at rest). In addition, muscle plays a central role in whole body protein metabolism and disrupted muscle metabolism is associated with the development of many common chronic diseases associated with obesity such as type 2 diabetes and cardiovascular disease. Although the contribution of disrupted muscle metabolism to chronic disease is well-established in older adults, the potential impact in children is unknown. The overall objective for this primary project application is to determine the role of breakfast protein consumption in improving energy metabolism, energy balance and skeletal muscle health in obese, school-aged children.

Conditions

• Body Weight Changes
• Body Composition
• Muscle Mass
• Energy Expenditure
• Nutrition

Interventions

OTHER

Carbohydrate

Participants will receive a carbohydrate-based breakfast beverage everyone morning for 42 days.

OTHER

Protein

Participants will receive a protein-based breakfast beverage everyone morning for 42 days.

Sponsors & Collaborators

• University of Arkansas

  collaborator OTHER

• University of Arkansas, Fayetteville

  lead OTHER

Principal Investigators

• Jamie I Baum, PhD · University of Arkansas

Study Design

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

DOUBLE

Model

PARALLEL

Eligibility

Min Age

7 Years

Max Age

14 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2018-06-21

Primary Completion

2019-09-15

Completion

2020-08-31

Countries

• United States

Study Locations