MedTrace Logo

Early Childhood Obesity Programming by Intrauterine Growth Restriction

NCT03402139 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 400

Last updated 2025-09-15

No results posted yet for this study

Summary

The molecular mechanisms underlying developmental programming of childhood obesity remain poorly understood. Here, the investigators address major questions about early childhood obesity programming by studying CD3+ T-cells from intrauterine growth restricted (IUGR) newborns who have an increased risk for obesity and other metabolic disorders in adult life.

Conditions

  • Childhood Obesity
  • Epigenetics

Sponsors & Collaborators

  • Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

    collaborator NIH

  • Icahn School of Medicine at Mount Sinai

    collaborator OTHER

  • Hackensack Meridian Health Center for Discovery and Innovation

    collaborator UNKNOWN

  • University of California, San Francisco

    collaborator OTHER

  • University of Wisconsin, Madison

    collaborator OTHER

  • Gencove

    collaborator UNKNOWN

  • Montefiore Medical Center

    lead OTHER

Principal Investigators

  • Sandra Reznik, MD · Montefiore Medical Center/Albert Einstein College of Medicine

Eligibility

Min Age
1 Hour
Max Age
24 Months
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-09-01
Primary Completion
2028-03-31
Completion
2028-03-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03402139 on ClinicalTrials.gov