Study to Determine if Serum BNP Levels Are Elevated in Pregnant Women With Pre-Eclampsia
NCT00533871 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 61
Last updated 2007-09-24
Summary
Preeclampsia is a common disease state occurring in the third trimester of pregnancy, with an incidence of approximately 5-10% in the US. Hypertension (high blood pressure), a primary symptom of pre-eclampsia, may be present in women who were hypertensive prior to becoming pregnant.B-type (also known as brain) natriuretic peptide (BNP) is known to be made and released from the heart ventricles when the heart is strained. There is also evidence that BNP is secreted in the placenta, and may increase in preeclampsia and chronic hypertension in pregnancy.The purpose of the study is to determine if a maternal blood sample analyzed for the quantity of BNP is helpful in differentiating between pre-eclampsia and chronic high blood pressure.
Conditions
Sponsors & Collaborators
-
Ohio State University
lead OTHER
Principal Investigators
-
Brian C Hiestand, MD · Ohio State University Department of Emergency Medicine
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2003-02-28
- Completion
- 2005-06-30
Countries
- United States
Study Locations
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