The Association Between Different Markers With Development of Maternal and Neonatal Complications in Women With Severe Preeclampsia
NCT07125599 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 284
Last updated 2025-08-27
Summary
pregnant women diagnosed with severe preeclampsia were subjected to • Full history taking including a detailed history of the hypertension state during the current pregnancy (onset, course, current medication, and whether the blood pressure is controlled or not).gravidity , parity mode of delivery any medical disorders, the presence of headache ,blurring of vision and epigastric pain.
* Complete physical examination: general (including BMI \& blood pressure measurement) and obstetric examinations.
* Routine obstetric ultrasound and Doppler indices Including umbilical artery Doppler (RI).
* Laboratory investigations :
1\. Complete blood count (CBC). 2 albuminuria will be detected by dipstick kits . 3. Liver enzymes \& kidney function. 4.PT,PC,INR.
* Pelvic-Abdominal ultrasound to assess the presence of ascites Ultrasound examination will be performed by a consultant obstetrician to detect free fluid in the peritoneal cavity, especially at hepato-renal pouch, sub-splenic area, or para-colic gutters.
The presence of ascites will be further confirmed at the time of delivery.
3-All labours will be attended by an expert neonatologist and the following will be recorded:
* APGAR score at (1 min).
* The further need for neonatal intensive care unit (NICU) admission.
* Perinatal death
Conditions
- Severe Preeclampsia
Sponsors & Collaborators
-
Cairo University
lead OTHER
Principal Investigators
-
Ahmed Maged, MD · Cairo University
Eligibility
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-05-02
- Primary Completion
- 2025-04-30
- Completion
- 2025-05-20
Countries
- Egypt
Study Locations
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