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Patient-ventilator Asynchrony in Patients With Brain Injury

NCT03212482 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2020-05-29

No results posted yet for this study

Summary

Mechanical ventilation is an important support strategy for critically ill patients. It could improve gas exchange, reduce the work of breathing, and improve patient comfort. However, patient-ventilator asynchrony, which defined as a mismatch between the patient and ventilator may obfuscate these goals. Studies have shown that a high incidence of asynchrony (asynchrony index \> 10%) is associated with prolonged mechanical ventilation and ICU length of stay and high mortality. So far, there have been only a few studies on the epidemiology of asynchrony in brain-injured patients. Investigators conduct a prospective observational study among brain-injured patients to determine the prevalence, risk factors and outcomes of patient-ventilator asynchrony. Esophageal pressure monitoring, a surrogate for pleural pressure, combined with airway pressure and flow waveforms is used to detect patient-ventilator asynchrony.

Conditions

  • Brain Injuries
  • Mechanical Ventilation

Sponsors & Collaborators

  • Jian-Xin Zhou

    lead OTHER

Principal Investigators

  • Jian-Xin Zhou, MD · Acute Brain Injury and Critical Care Research Collaboration, ABC Research Collaboration

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-06-15
Primary Completion
2019-07-01
Completion
2020-02-29

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03212482 on ClinicalTrials.gov