Linking Epidermal Barrier Function With Anti-Oxidant Defense Mechanisms in Skin Conditions
NCT03198390 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 100
Last updated 2021-06-04
Summary
Investigators will sample the skin and blood of patients with chronic skin conditions (including but not limited to atopic dermatitis (AD), contact dermatitis, hidradenitis suppurativa (HS), and psoriasis) to study the expression of anti-oxidative enzymes, skin barrier proteins and inflammatory molecules. In patients with atopic dermatitis, investigators will also measure skin barrier function using noninvasive devices. These results will be correlated with the disease severity in atopic dermatitis patients.
Conditions
- Atopic Dermatitis
- Hidradenitis Suppurativa
- Contact Dermatitis
- Psoriasis
Sponsors & Collaborators
-
University of Arizona
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 99 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2017-08-04
- Primary Completion
- 2020-05-31
- Completion
- 2020-05-31
Countries
- United States
Study Locations
More Related Trials
-
T Cell Repertoire Analysis of Immune Mediated Skin Diseases
NCT00368784 ·Status: COMPLETED
-
DERMATOMICS: Identifying Regulators of Skin Homeostasis
NCT06894654 ·Status: RECRUITING
-
Metabolic Profiling of Immune Responses in Immune-mediated Diseases
NCT04864886 ·Status: RECRUITING
-
A Pilot Cohort Study of Risk Factors and Novel Methods of Skin Lesion Assessments in Adults With Atopic Dermatitis, Alopecia Areata, Psoriasis or Vitiligo
NCT06319781 ·Status: RECRUITING
-
Effects of Oral Supplement Containing L-Histidine and Antioxidants on the Skin Barrier Function and Systemic Inflammation in Rosacea
NCT06072066 ·Status: RECRUITING ·Phase: NA
-
Activation of a Cutaneous Inflammasome in the Skin of Hidradenitis Suppurativa Patients
NCT02833909 ·Status: COMPLETED ·Phase: NA
-
Clinico-biological Collection of Autoimmune, Dysimmune or Auto-inflammatory Dermatological Diseases
NCT06387654 ·Status: RECRUITING
-
Effects of Topical SLPI on Skin Wounds
NCT00005569 ·Status: COMPLETED ·Phase: PHASE1
-
Methods Validation Assessment for Study of Inflammatory Skin Disease
NCT03796806 ·Status: COMPLETED
-
Baricitinib in the Treatment of Adults With Pyoderma Gangrenosum (PG)
NCT04901325 ·Status: COMPLETED ·Phase: PHASE2
-
China Type II Inflammatory Skin Disease Clinical Research and Standardized Diagnosis and Treatment Project
NCT05316805 ·Status: RECRUITING
-
TL1A Expression in Psoriatic Skin
NCT01744327 ·Status: UNKNOWN
-
Studies of Dermatologic Diseases Biospecimen Acquisition Protocol
NCT02471352 ·Status: RECRUITING
-
Genomic Research in Sarcoidosis
NCT01831739 ·Status: COMPLETED
-
NADPH Oxidase Correction in mRNA-transfected Granulocyte-enriched Cells in Chronic Granulomatous Disease (CGD)
NCT05189925 ·Status: RECRUITING ·Phase: PHASE1
-
Examination of Clinical and Laboratory Abnormalities in Patients With Defective DNA Repair: Xeroderma Pigmentosum, Cockayne Syndrome, or Trichothiodystrophy
NCT00001813 ·Status: COMPLETED
-
An Assessment of TLR4 and TOPK/PRPK Signaling in Sun Damaged Human Skin Acutely Exposed to Solar Simulated Light
NCT05398237 ·Status: COMPLETED ·Phase: NA
-
Retrospective Study of the Effects of Sub-pathologic Phenotypes of BP on Clinical Management and Prognosis
NCT06213909 ·Status: RECRUITING
-
Addressing Inequity in Dermatology
NCT06056648 ·Status: RECRUITING
-
Study of Scaling Disorders and Other Inherited Skin Diseases
NCT00001292 ·Status: COMPLETED
-
Analysis of Inflammation in the Vitiligo and Other Inflammatory Skin Diseases: Psoriasis, Atopic Dermatitis and Alopecia Areata
NCT03976622 ·Status: UNKNOWN
-
Use of an SPF30 Sunscreen and an After-sun-lotion in Skin Cancer Risk Patients
NCT00555633 ·Status: COMPLETED
-
Xeroderma Pigmentosum Patient Experiences
NCT01123694 ·Status: UNKNOWN
-
Optical Elastography of Systemic Sclerosis Skin
NCT02835196 ·Status: COMPLETED
-
Skin Tape Harvesting for Transcriptomics Analysis
NCT03048721 ·Status: COMPLETED ·Phase: NA