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Inflammatory and Cerebrospinal Biochemical Markers in Blood During Prolonged Hyperbaric Exposure

NCT03192930 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 26

Last updated 2019-04-09

No results posted yet for this study

Summary

Research hypothesis

* Prolonged hyperbaric exposure will affect the central nervous system
* Prolonged hyperbaric exposure will induce inflammatory changes
* Prolonged hyperbaric exposure will affect fluid regulation in the body

Objectives:

* To investigate the presence of cerebrospinal biochemical markers in blood during prolonged hyperbaric exposure
* To investigate changes in the quantity of cerebrospinal biochemical markers in blood during decompression after prolonged hyperbaric exposure
* To investigate the presence of inflammatory markers in blood during prolonged hyperbaric exposure
* To investigate changes in the quantity of inflammatory markers in blood during decompression after prolonged hyperbaric exposure
* To investigate if prolonged hyperbaric exposure alters fluid balance in the body

Conditions

  • Saturation Exposure
  • Decompression Injury

Interventions

OTHER

Hyperbaric exposure

Hyperbaric exposure 4 ATA for 36 hours followed by 70 hours decompression

Sponsors & Collaborators

  • Swedish Armed Forces Diving and Naval Medicine Centre

    collaborator OTHER

  • KTH Royal Institute of Technology

    collaborator OTHER

  • Sahlgrenska University Hospital

    lead OTHER

Principal Investigators

  • Henrik Zetterberg, PhD · Göteborg University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-03-17
Primary Completion
2018-01-17
Completion
2018-01-17

Countries

  • Sweden

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03192930 on ClinicalTrials.gov