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Cryptosporidium Infection and Human Colorectal Cancer

NCT04332705 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 324

Last updated 2023-11-18

No results posted yet for this study

Summary

It has been reported that Cryptosporidium parvum, a species of a protozoan frequently isolated from humans and animals, is able to induce digestive adenocarcinoma in a rodent model. Consistently, some epidemiological studies have reported an association with cryptosporidiosis in patients with colorectal adenocarcinoma. However, the correlation between cryptosporidiosis and human digestive cancer remains unclear at this time, and it is not known whether this intracellular parasite, considered an opportunistic agent, is able to induce gastrointestinal malignancies in humans. In order to add new arguments for a probable association between cryptosporidiosis and digestive human cancer, the main aim of this study is to determine prevalence and to identify species of Cryptosporidium among a French digestive cancer population.

Conditions

  • Colonic Neoplasms
  • Cryptosporidiosis

Interventions

DIAGNOSTIC_TEST

Detection of Cryptosporidium infection

A biopsy or a surgical sample will be collected from every participant

Sponsors & Collaborators

  • Institut Pasteur de Lille

    collaborator OTHER

  • Lille Catholic University

    lead OTHER

Principal Investigators

  • Bertrand Nunes, MD · GHICL

  • Gabriela Certad, MD, PhD · GHICL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-06-30
Primary Completion
2024-06-30
Completion
2024-12-30

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04332705 on ClinicalTrials.gov