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Theranova Dialyzer and Chronic Kidney Disease - Mineral Bone Disorder (CKD-MBD)

NCT03169400 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 20

Last updated 2017-05-30

No results posted yet for this study

Summary

The project will be structured in 3 main parts:

1. Effect of sera of ESRD patients on HD using Theranova dialyzer on high-Pi induced vascular calcification in an in vitro model of rat VSMCs.
2. Effect of sera of ESRD patients on HD using Theranova dialyzer on oxidative stress pathways in an in vitro model of rat VSMCs vascular calcification.
3. Study of RNA sequencing, transcriptome analysis gene expression of time course high-P challenged VSMCs studying the effect of sera of ESRD patients on HD using Theranova dialyzer

Conditions

  • End Stage Renal Failure on Dialysis
  • Vascular Calcification
  • Oxidative Stress

Interventions

DEVICE

Theranova dialyzer

Hemoadialysis

Sponsors & Collaborators

  • University of Milan

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-10-01
Primary Completion
2018-08-31
Completion
2018-12-31
FDA Device
Yes

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03169400 on ClinicalTrials.gov