Urgent-start Peritoneal Dialysis in ESRD Patients：A Multi-center Study

Summary

Within the last decade, urgent-start peritoneal dialysis(PD) has gained considerable interest amongst nephrologists. Several publications have provided assurances that urgent-start PD is indeed feasible and can serve patients well; however, most of the studies have small sample sizes, retrospective design, and the impact of the urgent-start dialysis modality on outcome, especially on short-term complications, has not been directly evaluated. Therefore, we started this multi-centered, prospective, interventional study compared the dialysis-related complications and survival rate directly between urgent-start PD and HD groups with a large sample to determine the feasibility and safety of urgent-start PD as an alternate initial modality of dialysis for patients who require urgent initiation of dialysis therapy.

Conditions

• End-Stage Renal Disease

Interventions

DEVICE

urgent-start peritoneal dialysis catheter

Patients initiated peritoneal dialysis as urgent-start dialysis modality with a peritoneal dialysis catheter.

DEVICE

central venous catheter

Patients initiated hemodialysis as urgent-start dialysis modality with a central venous catheter.

Sponsors & Collaborators

• Ruijin Hospital

  collaborator OTHER

• Xin Hua Hospital

  collaborator OTHER

• Shanghai Jiao Tong University Affiliated Sixth People's Hospital

  collaborator OTHER

• Changhai Hospital

  collaborator OTHER

• Shanghai University of Traditional Chinese Medicine

  collaborator OTHER

• Shanghai Tong Ren Hospital

  collaborator OTHER

• Shanghai Jiading District Central Hospital

  collaborator OTHER

• Shanghai Songjiang District Central Hospital

  collaborator UNKNOWN

• The Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine

  collaborator OTHER

• Shanghai Punan Hospital

  collaborator UNKNOWN

• RenJi Hospital

  lead OTHER

Principal Investigators

• Zhaohui Ni, Doctor · Renji Hospital, School of Medicine, Shanghai Jiao Tong University

• Gengru Jiang, Doctor · Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

• Niansong Wang, Doctor · The Sixth People's Hospital Affiliated to Shanghai Jiao Tong University

• Zhiyong Guo, Doctor · Changhai Hospital

• Xiaonong Chen, Doctor · Ruijin Hospital

• Feng Ding, Doctor · No.9 People Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

• Weijie Yuan, Doctor · Shanghai General Hospital affiliated to Shanghai Jiao Tong University

• Yueyi Deng, Doctor · Long Hua Hospital Shanghai University of Traditional Chinese Medicine

• Xiaoxia Wang · Tong Ren hospital Shanghai Jiao Tong university school of medicine

• Ying Li · Jiading district central hospital of Shanghai

• Xiujuan Zang · hanghai Songjiang District Central Hospital

• Guoqing Wu · The Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

80 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2019-02-26

Primary Completion

2021-11-17

Completion

2021-11-17

Countries

• China

Study Locations