Evaluation of Nutritional Status in Thalassemia Major Patients in Assiut Children Hospital
NCT03161899 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 246
Last updated 2020-07-30
Summary
Thalassemia is a blood disorder passed down through families in which the body makes an abnormal form of hemoglobin. There are 2 main types of thalassemia; Alpha \& Beta thalassemia. Alpha thalassemia: occurs when a gene or genes related to the alpha globin protein are missing or mutated.
Beta-thalassemia syndromes are a group of hereditary blood disorders characterized by reduced or absent beta globin chain synthesis. Beta-thalassemias can be classified into:
Silent carrier: completely asymptomatic with normal hematological parameters. Beta-thalassaemia minor (beta-thalassaemia trait): usually asymptomatic; diagnosis is made during a work-up for mild anemia.
Beta-thalassaemia intermedia: usually a similar presentation to beta-thalassaemia major; symptoms are usually less pronounced and the course is usually more insidious.
Beta-thalassaemia major : In which there is complete absence of hemoglobin A
Conditions
- Thalassemia Major
Sponsors & Collaborators
-
Assiut University
lead OTHER
Principal Investigators
-
asmaa refaat, MBBCH · Assuit , faculty of medicine, egypt
Eligibility
- Min Age
- 6 Years
- Max Age
- 14 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-12-15
- Primary Completion
- 2020-05-24
- Completion
- 2020-07-20
Countries
- Egypt
Study Locations
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