Erythrocyte Glutamine Level Relation to Pulmonary Hypertension Risk in Beta Thalassemia Major Children

NCT03133169 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 80

Last updated 2019-08-28

No results posted yet for this study

Summary

The study will investigate the relation between erythrocyte glutamine/glutamate ratio and pulmonary hypertension risk in Egyptian thalassemic children in Assiut University Children Hospital

Conditions

  • Thalassemia in Children
  • Pulmonary Hypertension
  • Hemolysis

Interventions

DIAGNOSTIC_TEST

blood sample

blood sample for measuring liver and kidney function, CBC, ferritin level and erythrocyte glutamine level

DIAGNOSTIC_TEST

Tricuspid regurge velocity

Tricuspid regurge velocity will be measured by doppler echocardiography denoting the pulmonary hypertension risk in children

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Principal Investigators

  • Fahim M Fahim, PhD · Children Hospital, Assiut University

  • Fatma S AbdElshafi, bachelor's · Children Hospital, Assiut University

  • Eman F. Mohamed, PhD · Children Hospital, Assiut University

Eligibility

Min Age
10 Years
Max Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-06-01
Primary Completion
2019-08-25
Completion
2019-08-26

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03133169 on ClinicalTrials.gov