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CLA and Vitamin D on Protein Turnover

NCT03115775 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2019-11-21

No results posted yet for this study

Summary

To conduct a randomized, double-blind, controlled clinical trial to determine the independent and combined effects of dietary conjugated linoleic acid (CLA) and vitamin D supplementation on anabolic signaling, the expression of growth regulatory factors, and muscle protein turnover in older adults.

Conditions

  • Protein

Interventions

DIETARY_SUPPLEMENT

Conjugated linoleic acid

Intervention will last up to 8 weeks. Subjects will receive conjugated linoleic acid (4000 mg Tonalin FFA 80) daily.

DIETARY_SUPPLEMENT

Vitamin D

Intervention will last up to 8 weeks. Subjects will receive vitamin D3 (2000 IU) daily.

DIETARY_SUPPLEMENT

Conjugated linoleic acid and Vitamin D

Intervention will last up to 8 weeks. Subjects will receive conjugated linoleic acid (4000 mg Tonalin FFA 80) and vitamin D3 (2000 IU) daily.

OTHER

Corn oil (placebo)

Intervention will last up to 8 weeks. Subjects will receive corn oil (4000 mg) daily.

Sponsors & Collaborators

  • BASF

    collaborator INDUSTRY

  • Washington University School of Medicine

    lead OTHER

Principal Investigators

  • Bettina Mittendorfer, PhD · Washington University School of Medicine

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
65 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-05-12
Primary Completion
2019-08-31
Completion
2019-08-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03115775 on ClinicalTrials.gov