Cell-free DNA Methylation Markers for Cancer Screening
NCT03096938 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 15000
Last updated 2017-12-27
Summary
The purpose of this study is to evaluate the role of cell-free DNA methylation markers in cancer screening.
Conditions
- Cancer Screening
Interventions
- DIAGNOSTIC_TEST
-
methylation markers screening
Cell-free DNA extraction from plasma samples-Bisulfite conversion of cfDNA-Determination of DNA methylation levels by deep sequencing-Sequencing data analysis
Sponsors & Collaborators
-
Sun Yat-sen University
lead OTHER
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- SCREENING
- Masking
- NONE
- Model
- CROSSOVER
Eligibility
- Min Age
- 40 Years
- Max Age
- 74 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2017-06-01
- Primary Completion
- 2020-10-01
- Completion
- 2021-05-01
Countries
- China
Study Locations
More Related Trials
-
Validation of DNA Methylation Biomarkers for Oral Cancer Detection
NCT02648789 ·Status: COMPLETED
-
DNA Methylation Biomarkers and Metastasis of Gastric Carcinoma
NCT02159339 ·Status: COMPLETED
-
Validation of DNA Methylation Biomarkers for Oral Cancer Detection-Follow up Study
NCT02902406 ·Status: UNKNOWN
-
Use of Plasma ctDNA Methylation Haplotypes in Detecting Local Residual or Lymph Node Metastasis
NCT03868215 ·Status: UNKNOWN
-
Investigating Multigene Methylation Dynamics in Treatment Response Surveillance for Gastric Cancer
NCT06979895 ·Status: NOT_YET_RECRUITING
-
Development of Free DNA Multi-target Methylated PCR for Auxiliary Diagnosis of Gastric Cancer
NCT05336058 ·Status: COMPLETED
-
Exploration and Verification of DNA Methylolation in Early Screening of Esophageal Cancer
NCT03922230 ·Status: UNKNOWN
-
Assessment of Early Detection and Prognosis Based on cfDNA Methylation in Multiple Myeloma
NCT05693012 ·Status: UNKNOWN
-
Cell-free DNA Methylation for Epithelial Ovarian Cancer
NCT04651946 ·Status: UNKNOWN ·Phase: PHASE2
-
Identifying MSI Status From ctDNA in Chinese Patients With Refractory Advanced Solid Tumors
NCT03596593 ·Status: UNKNOWN ·Phase: NA
-
Plasma ctDNA Detection in Diagnosis of Epithelial Ovarian Cancer.
NCT03155451 ·Status: COMPLETED
-
Development of a Cell Free DNA Assay as a Biomarker for Predicting Early Non-response to Therapy in Metastatic Cancer
NCT03892096 ·Status: COMPLETED
-
Early Diagnosis of Oral Cancer by Detecting p16 Methylation
NCT01695018 ·Status: COMPLETED
-
(COVID-19) Longitudinal Neutralizing Antibody Titers in Cancer Patients Receiving Different Anti-caner Therapies
NCT05384509 ·Status: RECRUITING
-
DNA in Predicting Response After Systemic Therapy in Women With Metastatic Breast Cancer
NCT00899548 ·Status: COMPLETED
-
Prospective Screening and Differentiating Common Cancers Using Peripheral Blood Cell-Free DNA Sequencing
NCT06036563 ·Status: RECRUITING
-
Pan-canceR Early DetectIon projeCT (PREDICT)
NCT04817306 ·Status: UNKNOWN
-
HCC Screening Using DNA Methylation Changes in ctDNA
NCT03483922 ·Status: COMPLETED
-
Performance Evaluation of Urine DNA Methylation Testing for the Detection of Urothelial Carcinoma in Patients With Hematuria
NCT06469229 ·Status: NOT_YET_RECRUITING
-
ctDNA Methylation for Epithelial Ovarian Cancer
NCT05801263 ·Status: RECRUITING
-
Circulating Tumor DNA (ctDNA) Monitoring in the Assessment and Prediction of the Efficacy of PARP Inhibitors (PARPi)
NCT05116579 ·Status: RECRUITING
-
CtDNA as a Novel Biomarker of Treatment Efficacy in Patients With Ovarian Cancer
NCT05027828 ·Status: RECRUITING
-
Gastric Cancer Early Detection by Multi-dimensional Analysis of cfDNA
NCT05668910 ·Status: UNKNOWN
-
Genomics and Prognosis in GI Cancers
NCT05767697 ·Status: RECRUITING
-
Genotyping 2 SNPs in Chinese Breast Cancers
NCT02886845 ·Status: UNKNOWN