DNA Methylation Biomarkers and Metastasis of Gastric Carcinoma

NCT02159339 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 198

Last updated 2015-06-19

No results posted yet for this study

Summary

Gastric carcinoma (GC) is the second leading cause of cancer death throughout the world. In previous multi-center study, we have found that the prevalence of GDNF family receptor alpha 1(GFRA1), serum response factor (SRF), and ZNF382 methylation alterations were inversely and coordinately associated with GC metastasis and the patients' overall survival throughout discovery and testing cohorts in China, Japan and Korea. The present cohort study is to investigate whether methylation of those genes can predict the metastasis and prognosis of GC.

Conditions

  • Gastric Carcinoma

Sponsors & Collaborators

  • Peking University

    collaborator OTHER
  • Peking University Cancer Hospital & Institute

    lead OTHER

Principal Investigators

  • Dajun Deng, Master · Peking University Cancer Hospital & Institute

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-12-31
Primary Completion
2015-06-30
Completion
2015-06-30

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02159339 on ClinicalTrials.gov