DNA Methylation Biomarkers and Metastasis of Gastric Carcinoma
NCT02159339 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 198
Last updated 2015-06-19
Summary
Gastric carcinoma (GC) is the second leading cause of cancer death throughout the world. In previous multi-center study, we have found that the prevalence of GDNF family receptor alpha 1(GFRA1), serum response factor (SRF), and ZNF382 methylation alterations were inversely and coordinately associated with GC metastasis and the patients' overall survival throughout discovery and testing cohorts in China, Japan and Korea. The present cohort study is to investigate whether methylation of those genes can predict the metastasis and prognosis of GC.
Conditions
- Gastric Carcinoma
Sponsors & Collaborators
-
Peking University
collaborator OTHER -
Peking University Cancer Hospital & Institute
lead OTHER
Principal Investigators
-
Dajun Deng, Master · Peking University Cancer Hospital & Institute
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2012-12-31
- Primary Completion
- 2015-06-30
- Completion
- 2015-06-30
Countries
- China
Study Locations
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