Identifying MSI Status From ctDNA in Chinese Patients With Refractory Advanced Solid Tumors
NCT03596593 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 8000
Last updated 2018-07-24
Summary
This is a molecular epidemiological investigation aiming to identify microsatellite instability status from circulating tumor DNA in Chinese patients with refractory advanced solid tumors.
Conditions
Interventions
- DIAGNOSTIC_TEST
-
SPANOM (identifying MSI status from ctDNA)
SPANOM technique, which has been developed by 3D Medicines Inc. Shanghai, China and made it possible to identify MSI status from blood samples, will be used in patients with refractory advanced solid tumors.
Sponsors & Collaborators
-
Peking University
lead OTHER
Principal Investigators
-
Shen Lin, Professor · Peking University
Study Design
- Allocation
- NA
- Purpose
- DIAGNOSTIC
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-07-11
- Primary Completion
- 2020-06-30
- Completion
- 2020-06-30
Countries
- China
Study Locations
More Related Trials
-
MSI in Circulatory DNA of Endometrial Cancer
NCT03744962 ·Status: UNKNOWN
-
ctDNA-MRD Monitoring After Resection in Gastric Cancer
NCT06893133 ·Status: RECRUITING
-
Use of Plasma ctDNA Methylation Haplotypes in Detecting Local Residual or Lymph Node Metastasis
NCT03868215 ·Status: UNKNOWN
-
Prospective Screening and Differentiating Common Cancers Using Peripheral Blood Cell-Free DNA Sequencing
NCT06036563 ·Status: RECRUITING
-
Clinical Benefit of Genetic Biomarkers for Guiding Treatment Decisions in Oncology Drugs
NCT02458040 ·Status: WITHDRAWN
-
Cell-free DNA Methylation Markers for Cancer Screening
NCT03096938 ·Status: UNKNOWN ·Phase: NA
-
Inherited Susceptible Genes Among Epithelial Ovarian Cancer
NCT03015376 ·Status: UNKNOWN
-
Liquid Biopsy in Monitoring the Therapeutic Efficacy of Targeted Therapy in Advanced/Metastatic Gastric Cancer
NCT02610218 ·Status: UNKNOWN
-
Real-time Monitoring of Concentration and Size Variations of Circulating Plasma Free DNA to Predict Early Response to Immunotherapies in Patients With Different Types of Cancer.
NCT05083494 ·Status: UNKNOWN
-
Potential Clinical Utilities of Circulating Tumor DNA in Advanced HER2 Negative Gastric Cancer
NCT05513144 ·Status: UNKNOWN
-
The Dynamic Monitoring of Cerebrospinal Fluid ctDNA
NCT06315686 ·Status: RECRUITING ·Phase: PHASE2
-
Development of Free DNA Multi-target Methylated PCR for Auxiliary Diagnosis of Gastric Cancer
NCT05336058 ·Status: COMPLETED
-
Identification of Marker of Primary or Acquired Resistance to Anti Tumorous Treatment
NCT02105168 ·Status: UNKNOWN ·Phase: NA
-
Detection of CSF Next Generation Sequencing in the Application of Brain Metastases From Lung Adenocarcinoma or Meningeal Metastasis
NCT03029065 ·Status: UNKNOWN
-
DNA Methylation Biomarkers and Metastasis of Gastric Carcinoma
NCT02159339 ·Status: COMPLETED
-
Taiwan Cancer Moonshot Project
NCT05248763 ·Status: RECRUITING
-
Detection of G-quadruplex DNA Methylation in Cancer
NCT06537063 ·Status: WITHDRAWN
-
Screening Study for Participants With Malignant Tumors
NCT05419375 ·Status: COMPLETED ·Phase: PHASE2
-
Assessment of the Minimal Residual Disease in Ovarian Cancer From Circulating Tumor DNA and Immune Repertoire
NCT03614689 ·Status: ACTIVE_NOT_RECRUITING
-
Renal Cancer Monitoring Based on ctDNA Methylomics: A Prospective Cohort Study (MEMORY Study)
NCT05917106 ·Status: RECRUITING
-
Target Gene Sequencing for Advanced Stage, Relapsed or Refractory Natural Killer/T-cell Lymphoma
NCT04509804 ·Status: COMPLETED
-
The Registration Program of BRCA1/2 Gene
NCT02593435 ·Status: UNKNOWN
-
Mechanism and Immune Function Analysis of SARS-CoV-2 Infection in Hematologic Tumors
NCT05683353 ·Status: ACTIVE_NOT_RECRUITING
-
Prospective Multi-omics Observational Study of Gynecological Rare Pathological Tumors
NCT05985941 ·Status: NOT_YET_RECRUITING
-
Plasma ctDNA Detection in Diagnosis of Epithelial Ovarian Cancer.
NCT03155451 ·Status: COMPLETED