Patient-Driven Transfusion Thresholds in Hematological Disorders: A Pilot Study
NCT03086252 · Status: WITHDRAWN · Phase: NA · Type: INTERVENTIONAL
Last updated 2018-07-26
Summary
This pilot study evaluates safety of administration of red blood cell transfusions requested by patients based on their symptoms instead of levels of hemoglobin for the treatment of chronic anemia in patients with blood disorders.
Conditions
- Anemia
- Aplastic Anemia
- Bone Marrow Failure
- Hematopoietic and Lymphoid Cell Neoplasm
- Leukemia
- Myelodysplastic Syndrome
Interventions
- PROCEDURE
-
Red Blood Cell Transfusions (RBCT)
Undergo patient-driven RBCT
Sponsors & Collaborators
-
Emory University
lead OTHER
Principal Investigators
-
Ana Antun, MD · Emory University
Study Design
- Allocation
- NA
- Purpose
- SUPPORTIVE_CARE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 19 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-07-24
- Primary Completion
- 2018-05-31
- Completion
- 2018-05-31
Countries
- United States
Study Locations
More Related Trials
-
Transfusion Effects in Myelodysplastic Patients: Limiting Exposure
NCT00202371 ·Status: WITHDRAWN ·Phase: PHASE4
-
Early Detection of Graft-Versus-Host Disease in Patients Undergoing a Donor Bone Marrow Transplant
NCT00898612 ·Status: WITHDRAWN
-
Study of Low Intensity Conditioning and Immunotherapy for High-Risk Cancers of the Blood
NCT00143884 ·Status: TERMINATED ·Phase: PHASE2
-
Maintaining a Higher Level of Haemoglobin: Effect on the White Cells After Bone Marrow Transplantation in Children.
NCT00937053 ·Status: TERMINATED ·Phase: PHASE2
-
Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders
NCT03128996 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Prevention of Graft-Versus-Host Disease in Patients Undergoing Bone Marrow Transplantation
NCT00003538 ·Status: COMPLETED ·Phase: NA
-
Physiologic Effects of RBC Transfusion
NCT02566577 ·Status: TERMINATED ·Phase: PHASE4
-
Donor T Cells in Treating Patients With High-Risk Hematologic Cancer Undergoing Donor Peripheral Blood Stem Cell Transplant
NCT00725062 ·Status: TERMINATED ·Phase: PHASE1
-
Autologous Tregs for Aplastic Anaemia
NCT05386264 ·Status: RECRUITING ·Phase: PHASE1
-
Phase I Clinical Study of Haplo-HSCT Combined With Hypoxic 3D-Cultured Umbilical Cord MSC for the Treatment of SAA
NCT07299123 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE1/PHASE2
-
Haploidentical Transplantation With Pre-Transplant Immunosuppressive Therapy for Patients With Sickle Cell Disease
NCT03279094 ·Status: RECRUITING ·Phase: PHASE1
-
A Comparison of Dendritic Cell Content and T-Cell Phenotype Between Granulocyte Colony-Stimulating Factor (G-CSF) or G-CSF + Granulocyte Macrophage (GM)-CSF
NCT00208949 ·Status: TERMINATED ·Phase: PHASE2
-
Effect of NAC on the Hematopoietic Reconstitution After Haploidentical Hematopoietic Stem Cell Transplantation
NCT03236220 ·Status: COMPLETED ·Phase: PHASE2
-
Kidney and Hematopoietic Cell Transplants Using a Regimen to Promote Hematopoietic Cell Engraftment
NCT04571203 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE1
-
Evaluation of Loratadine for G-CSF Induced Bone Pain in Patients With Hematologic Malignancies
NCT02305979 ·Status: COMPLETED
-
Evaluation, Treatment, and Training for Patients With Blood Disorders
NCT00001397 ·Status: COMPLETED
-
Risk Stratification-directed NAC for Prevention of Poor Hematopoietic Reconstitution
NCT03967665 ·Status: UNKNOWN ·Phase: PHASE3
-
Bilateral Orthotopic Lung Transplant - Bone Marrow Transplant
NCT03330795 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Long-Term Follow-up of People Undergoing Hematopoietic Stem Cell Transplantation
NCT03000244 ·Status: RECRUITING
-
Prospective Cohort for the Evaluation of Biomarkers Following HCT (BMT CTN 1202)
NCT01879072 ·Status: COMPLETED
-
Mesenchymal Stromal Cells for Haplo Hematopoietic Cell Transplantation for Sickle Cell Disease
NCT03298399 ·Status: WITHDRAWN ·Phase: PHASE1
-
In-Vitro Studies in Depletion of Haplotype Mismatched Alloreactive T Cells
NCT00731705 ·Status: WITHDRAWN
-
Supportive Care for Patients With Hematological Malignancies Undergoing Hematopoietic Cell Transplant
NCT01758484 ·Status: COMPLETED ·Phase: NA
-
Retrospective Study of Viral Reactivation Across All Bone Marrow Transplant Protocols Since 2010
NCT03111745 ·Status: COMPLETED
-
Natural History and Biology of Long-Term Late Effects Following Hematopoietic Cell Transplant for Childhood Hematologic Malignancies
NCT02338479 ·Status: UNKNOWN