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PERIODONTITIS AND VASCULAR DYSFUNCTION

NCT03072342 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 190

Last updated 2021-01-25

No results posted yet for this study

Summary

The investigators wish to assess whether intensive periodontal therapy will reduce the burden of chronic periodontal disease and will cause regression or prevent progression of atherosclerosis assessed by a surrogate end-point (carotid intima-media thickness) at 24 months compared to control periodontal therapy.

Conditions

  • Periodontitis
  • Intimal Medial Thickness of Internal Carotid Artery

Interventions

PROCEDURE

Intensive Periodontal Treatment

PROCEDURE

Control Periodontal Treatment

Sponsors & Collaborators

  • University College, London

    lead OTHER

Principal Investigators

  • John Deanfield, MD · UCL

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-04-16
Primary Completion
2020-03-30
Completion
2020-03-30

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03072342 on ClinicalTrials.gov