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Synovial Aspiration and Serological Testing in Two-stage Revision Arthroplasty of Prosthetic Joint Infection

NCT03038464 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 40

Last updated 2017-04-25

No results posted yet for this study

Summary

The two-stage protocol is gold standard in terms of infection control treating prosthetic joint infections of total hip and total knee arthroplasty. The antibiotic pause for diagnostic reasons before reconstruction (stage two) is discussed concerning persistence of infection and development of resistant bacterial strains. Serological markers and synovial analysis are common use to exclude persistence of infection.

The investigators therefore asked 1) is the serological testing of c-reactive protein and leukocytes a valuable tool to predict a persistence of infection and 2) what is the role of synovial aspiration of PMMA Spacers on hip and knee joints.

Conditions

  • Diagnosis Prosthetic Joint Infection

Interventions

DIAGNOSTIC_TEST

Synovial biopsy

Biopsy of jint prior reimplantation of new joint prosthesis

Sponsors & Collaborators

  • Technical University of Munich

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-11-01
Primary Completion
2019-04-01
Completion
2019-05-01

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03038464 on ClinicalTrials.gov