MedTrace Logo

Intraoperative Goal Directed Fluid Management in Supratentorial Brain Tumor Craniotomy

NCT03033706 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 61

Last updated 2018-11-23

No results posted yet for this study

Summary

Pulse pressure variation (PPV) to standard fluid management (4ml/Kg/hr) in patients undergoing supratentorial mass excision. The investigators hypothesize that in these procedures, goal-directed fluid therapy (GDT) might improve brain relaxation, and patient hemodynamics intra and postoperatively.

Conditions

Interventions

PROCEDURE

Pulse pressure variation guided fluid therapy

Pulse pressure variation obtained from invasive blood pressure waveform

PROCEDURE

Traditional fluid therapy

4 ml/Kg/hr ringer solution plus rescue fluid bolus of 200 ml Ringer solution if Mean arterial pressure decreased by 20% with central venous pressure less than 4 mmHg.

PROCEDURE

Brain tumor excision

Brain tumor excision under general anesthesia

Sponsors & Collaborators

  • Cairo University

    lead OTHER

Principal Investigators

  • Ahmed Mukhtar, Professor · Head of research committee section in anesthesia department

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-03-25
Primary Completion
2018-01-25
Completion
2018-01-30

Countries

  • Egypt

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03033706 on ClinicalTrials.gov