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Two Cut-Off Values of Plethysmographic Variability Index to Guide Intraoperative Fluid Therapy on Serum Lactate in Patients Undergoing Excision of Supra-Tentorial Brain Tumors

NCT07174128 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 32

Last updated 2026-04-21

No results posted yet for this study

Summary

This study aimed to compare two cut-off values of plethysmographic variability index (PVI) -guided fluid therapy in patients undergoing supra-tentorial mass excision regarding immediate postoperative serum lactate.

Conditions

  • Cut-Off Value
  • Plethysmographic Variability Index
  • Intraoperative
  • Fluid Therapy
  • Serum Lactate
  • Excision
  • Supra-Tentorial Brain Tumors

Interventions

OTHER

Fluid Therapy

Patients would receive the second round of fluid loading if the Plethysmographic Variability Index (PVI) was 14%.

OTHER

Fluid Therapy

Patients would receive the second round of fluid loading if the Plethysmographic Variability Index (PVI) was 20%.

Sponsors & Collaborators

  • Cairo University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-09-20
Primary Completion
2026-02-24
Completion
2026-02-24

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07174128 on ClinicalTrials.gov