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The Cognitive Resilience Study

NCT03016702 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 29

Last updated 2017-08-14

No results posted yet for this study

Summary

The purpose of this study is to test whether two new cognitive "stress tests" may help distinguish between people at lower or higher genetic risk of Alzheimer's Disease. The investigators are trying to understand how these cognitive "stress tests" work in people who have not been diagnosed with Alzheimer's Disease and are not exhibiting symptoms of Alzheimer's Disease. Study subjects will undergo testing of memory and executive function during functional magnetic resonance image (fMRI) of the brain and also during a walking test.

Conditions

  • Alzheimer Disease

Interventions

OTHER

Cognitive stress tests during functional MRI

Subjects will undergo progressively more complex cognitive stress tests that assess memory and executive function while undergoing fMRI.

OTHER

Cognitive stress tests during gait task

Subjects will undergo progressively more complex cognitive stress tests that assess memory and executive function both in sitting and while ambulating on a force sensor mat.

Sponsors & Collaborators

  • National Institute on Aging (NIA)

    collaborator NIH

  • Bryan Alzheimer's Disease Research Center

    collaborator UNKNOWN

  • Duke University Center for the Study of Aging and Human Development

    collaborator UNKNOWN

  • Duke University

    lead OTHER

Principal Investigators

  • Heather Whitson, MD, MHS · Duke University Aging Center

Study Design

Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
58 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-02-27
Primary Completion
2017-08-09
Completion
2017-08-09

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03016702 on ClinicalTrials.gov