Open Versus Laparoscopic Left-sided Hepatectomy Trial

Summary

Open versus Laparoscopic Left-sided Hepatectomy (OLLEH) trial Multi-institutional, prospective and randomized trial in patients undergoing left sided hepatectomy through laparoscopic versus open procedure.

Primary endpoint: Functional recovery Secondary endpoint: Hospital duration, estimated blood loss, operation time, resection margin status, postoperative complication, mortality, liver function laboratory test, re-admission, quality of life, cosmesis, cost effectiveness

Conditions

• Neoplasm, Liver

Interventions

PROCEDURE

Open left-sided hepatectomy

Open left-sided hepatectomy Laparotomy (upper midline, inverted 'L', or Benz incision) Mobilization of the liver Glissonian approach or individual isolation technique Left lateral sectionectomy or left hemihepatectomy

PROCEDURE

Laparoscopic left-sided hepatectomy

Trocar insertion Mobilization of the liver Glissonian approach or individual isolation technique Left lateral sectionectomy or left hemihepatectomy

Sponsors & Collaborators

• Korea Cancer Center Hospital

  collaborator OTHER

• Seoul National University Boramae Hospital

  collaborator OTHER

• Eulji University Hospital

  collaborator OTHER

• Bucheon St. Mary's Hospital

  collaborator OTHER

• Gyeongsang National University Hospital

  collaborator OTHER

• Jeju National University Hospital

  collaborator OTHER

• The Catholic University of Korea

  collaborator OTHER

• Soonchunhyang University Hospital

  collaborator OTHER

• Inje University

  collaborator OTHER

• Pusan National University Hospital

  collaborator OTHER

• DongGuk University

  collaborator OTHER

• Chung-Ang University Hosptial, Chung-Ang University College of Medicine

  collaborator OTHER

• Chonnam National University Hospital

  collaborator OTHER

• Hallym University Kangnam Sacred Heart Hospital

  collaborator OTHER

• Hallym University Medical Center

  collaborator OTHER

• Seoul St. Mary's Hospital

  collaborator OTHER

• Ewha Womans University Mokdong Hospital

  lead OTHER

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

80 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2017-01-31

Primary Completion

2019-12-31

Completion

2021-12-31

Countries

• South Korea

Study Locations