MedTrace Logo

Dose-response of Ketamine in Patient Controlled Analgesia in Orthopaedic Surgery Patients

NCT02994173 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2019-12-11

No results posted yet for this study

Summary

To study the multimodal protocol combining adjunct ketamine with oxycodone in intravenous patient-controlled analgesia bolus dosing and effects in patients scheduled for posterolateral lumbar spine fusion with bilateral transpedicular screw instrumentation

Conditions

  • Pain, Postoperative

Interventions

DRUG

Oxycodone

Current clinical practice, used as a control in this study

DRUG

S-Ketamine 0.25

dosage

DRUG

S-Ketamine 0.5

dosage

DRUG

S-Ketamine 0.75

dosage

Sponsors & Collaborators

  • University of Turku

    collaborator OTHER

  • University of Helsinki

    collaborator OTHER

  • Turku University Hospital

    lead OTHER_GOV

Principal Investigators

  • Marko Peltoniemi, MD, PhD · Perioperative Services, Intensive Care and Pain Therapy, Turku University Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-02-01
Primary Completion
2019-11-03
Completion
2019-12-05

Countries

  • Finland

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02994173 on ClinicalTrials.gov