Study on the Neurovascular Coupling Function in Patients Undergoing Cardiac Surgery
NCT02977455 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 30
Last updated 2016-11-30
Summary
Existing researches show that brain is an organ highly dependent on continuous blood supply. Energy and oxygen required for normal physiological activities in the brain are stably maintained by a neurovascular regulatory mechanism, also known as functional congestion. While under pathological condition such as ischemia, this regulatory mechanism would be impaired and brain function loss and tissue damage occur. During anesthesia in cardiac surgery, inevitable circulatory fluctuations could result in decreasing blood pressure and cerebral blood flow and therefore brain tissue is in ischemia. In this situation the neurovascular regulatory mechanism will function and the brain oxygen saturation also changes based on how this mechanism is influenced. the investigators were devoted to observe how this mechanism was influenced during surgery and how the neural function recovers after surgery so to explore the relationship between them.
Conditions
- Neurovascular Coupling Mechanism and Cognitive Function
Sponsors & Collaborators
-
Xiangya Hospital of Central South University
lead OTHER
Eligibility
- Min Age
- 2 Years
- Max Age
- 12 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-10-31
- Primary Completion
- 2017-03-31
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