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Effect of Enamel Matrix Proteins on Clinical Attachment Level and Alveolar Bone in Periodontal Maintenance Patients

NCT02972788 · Status: COMPLETED · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2023-12-01

No results posted yet for this study

Summary

The purpose of the study is to determine the effect of enamel matrix protein derivative on an inflamed, periodontal-involved tooth. The hypothesis to be studied is that enamel matrix derivative protein with increase the clinical attachment level is localized sites of advanced periodontal disease.

Conditions

  • Periodontal Bone Loss

Interventions

DRUG

Enamel Matrix Proteins Derivative

Enamel matrix proteins derivative will be placed in deep periodontal pocket during routine periodontal maintenance therapy.

OTHER

Saline

Saline will be placed in deep periodontal pocket during routine periodontal maintenance therapy.

Sponsors & Collaborators

  • University of Nebraska

    lead OTHER

Principal Investigators

  • Amy Killeen, DDS, MS · University of Nebraska

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-02-01
Primary Completion
2018-09-20
Completion
2018-09-20
FDA Drug
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02972788 on ClinicalTrials.gov