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Randomized Clinical Trial of Enamel Matrix Derivative: Radiographic Analysis

NCT02195765 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 48

Last updated 2014-07-21

No results posted yet for this study

Summary

This is a split-mouth, double-blind randomized controlled trial. Computerized linear radiographic measurements were used to detect infrabony defects treated with open flap debridement (OFD) or OFD associated with enamel matrix derivative (EMD), after 24 months. Ten patients presenting 2 or more defects were selected (43 defects). An individualized film holder was used to take standardized radiographs at baseline and after 24 months. Images were digitized and used to measure the distances from the cemento-enamel junction (CEJ) to the alveolar crest (AC), CEJ to the bottom of the defect (BD) and infrabony defect angle.

Conditions

  • Chronic Periodontitis

Interventions

DRUG

enamel matrix derivative

Open flap debridement associated with enamel matrix derivative

PROCEDURE

Open flap debridement

Open flap debridement

Sponsors & Collaborators

  • University of Sao Paulo

    lead OTHER

Principal Investigators

  • Luiz Antonio PA Lima, Associate · University of Sao Paulo

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2002-06-30
Primary Completion
2004-10-31
Completion
2005-10-31

Countries

  • Brazil

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02195765 on ClinicalTrials.gov