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Neutrophil Extracellular Trap Formation in Patients Undergoing Bone Marrow Transplant

NCT01735565 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 23

Last updated 2016-08-11

No results posted yet for this study

Summary

This is a prospective observational study to determine the point after bone marrow transplant in adults and children at which the neutrophils derived from the transplanted stem cells are competent to form functional neutrophil extracellular traps (NETs). Furthermore, given the importance of platelet function for NET formation, we also plan to examine platelet activation and function as well as the platelet transcriptome using the same clinical samples.

Conditions

  • Bone Marrow Transplant

Sponsors & Collaborators

  • Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

    collaborator NIH

  • University of Utah

    lead OTHER

Principal Investigators

  • Christian Yost, MD · University of Utah

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-06-30
Primary Completion
2014-03-31
Completion
2016-07-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01735565 on ClinicalTrials.gov