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Brain-oscillation Synchronised Stimulation of the Prefrontal Cortex

NCT02920840 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 17

Last updated 2020-09-09

No results posted yet for this study

Summary

Combining TMS and EEG, this study investigates a personalized therapeutic non-invasive brain stimulation protocol in patients with major depression, whereby the timing of the TMS pulses is synchronized with the instantaneous phase of ongoing brain oscillations in order to modulate the inter-hemispheric left and right dorso-lateral prefrontal cortical brain network.

Conditions

Interventions

DEVICE

Intermittent theta-burst stimulation

see associated arm/group description

DEVICE

Negative-peak-triggered-TMS

see associated arm/group description

DEVICE

Open-loop replay TMS

see associated arm/group description

Sponsors & Collaborators

  • University Hospital Tuebingen

    lead OTHER

Principal Investigators

  • Brigitte Zrenner, MD · University Neurology Hospital Tübingen

  • Florian Müller-Dahlhaus, MD · University Neurology Hospital Tübingen

  • Ulf Ziemann, MD · University Neurology Hospital Tübingen

  • Andreas J Fallgatter, MD · University Psychiatry Hospital Tübingen

  • Surjo Soekadar, MD · University Psychiatry Hospital Tübingen

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-09-30
Primary Completion
2017-04-30
Completion
2017-04-30

Countries

  • Germany

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02920840 on ClinicalTrials.gov