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Prevalence of Spontaneous Pneumothorax in BHD

NCT02916992 · Status: UNKNOWN · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 200

Last updated 2016-10-26

No results posted yet for this study

Summary

To assess the prevalence of BHD (Birt-Hogg-Dubé syndrome) among patients with spontaneous pneumothorax. Patients who were treated for primary spontaneous pneumothorax in Rijnstate hospital are to be included. Patients will receive a questionnaire. When given consent, the investigators will invite them for a one-time visit to the out-patient clinic. Patients will be asked for a blood sample to determine pathogenic FLCN (folliculin) mutations and a pulmonary CT scan for evaluation of presence of lung cysts.

Conditions

  • Spontaneous Pneumothorax

Interventions

RADIATION

CT scan of the thorax

A low dose CT scan of the thorax (2mSv) wil be performed once.

GENETIC

blood sample for FLCN mutation analyses

A venous punction in order to withdraw 16ml blood is undertaken once.

Sponsors & Collaborators

  • Prof. Dr. Jaap Swieringa stichting

    collaborator UNKNOWN

  • Mr. Willem Bakhuys Roozeboomstichting

    collaborator UNKNOWN

  • Rijnstate Hospital

    collaborator OTHER

  • Hans Smit

    lead OTHER

Principal Investigators

  • Pieter E. Postmus, MD, PhD · The Clatterbridge Cancer Centre

  • Hans JM Smit, MD, PhD · Rijnstate Hospital

Study Design

Allocation
NON_RANDOMIZED
Purpose
SCREENING
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-09-30
Primary Completion
2017-06-30
Completion
2017-07-31

Countries

  • Netherlands

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02916992 on ClinicalTrials.gov