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Evaluation of Non-invasive Measurements of Atherosclerosis in Cardiovascular Risk Stratification

NCT01555294 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 1960

Last updated 2012-03-15

No results posted yet for this study

Summary

Multiple risk factors contribute to atherosclerosis, which ultimately results in clinical manifestation of cardiovascular disease. Atherosclerosis results in both functional and morphological changes in the vessel wall, which can be measured by ultrasonography. The current study has been designed to

1. To evaluate whether non-invasive measurements of atherosclerosis are independent predictors of cardiovascular disease and
2. to delineate new biochemical parameters and genetic variations, allowing earlier and more effective preventive therapy
3. The investigators intend to set guidelines for use of NIMA in an outpatient setting to facilitate early detection of increased cardiovascular risk and monitor life-style and pharmaceutical interventions.

In both the general population and in Familial Combined Hyperlipidemia.

Conditions

Sponsors & Collaborators

  • Radboud University Medical Center

    lead OTHER

Principal Investigators

  • Jacqueline de Graaf, MD, PhD · Radboud University Nijmegen Medical Centre, Dept. of General Internal Medicine, Division of Vascular Medicine

  • Anton FH Stalenhoef, MD, PhD · Radboud University Nijmegen Medical Centre, Dept. of General Internal Medicine, Division of Vascular Medicine

  • Martin den Heijer, MD, PhD · Radboud University Nijmegen Medical Centre, Dept. of Epidemiology and Biostatistics

  • Suzanne Holewijn, PhD · Radboud University Nijmegen Medical Centre, Dept. of General Internal Medicine, Division of Vascular Medicine

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2005-05-31
Primary Completion
2011-05-31
Completion
2011-05-31

Countries

  • Netherlands

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01555294 on ClinicalTrials.gov