Study on Genetically Affected Sporadic Thoracic Aortic Aneurysm and Dissection
NCT02852603 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 450
Last updated 2021-04-13
Summary
Mortality of thoracic aortic aneurysm and dissection (TAAD) remains high because of the huge blood lost from the aorta. Questions about the potentially genetic effects on sporadic TAAD are raised by researchers to explore the possible mechanisms leading to sporadic TAAD and to establish new clinical approaches to prevent TAAD-caused adverse clinical outcomes. This study is intended to collect the gene information in sporadic TAAD patients and to explore the relationship between genetic variation and the incidence of sporadic TAAD for further study.
Conditions
- Dissection of Aorta, Thoracic
- Aneurysm of Aorta, Thoracic
Sponsors & Collaborators
-
Fu Wai Hospital, Beijing, China
collaborator OTHER -
Wuhan Asia Heart Hospital
lead OTHER
Principal Investigators
-
Xuan Zheng, MD, PhD · Wuhan Asia Heart Hospital
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-08-31
- Primary Completion
- 2019-01-31
- Completion
- 2020-01-31
Countries
- China
Study Locations
More Related Trials
-
Genetic Basis of Abdominal Aortic Aneurysm
NCT00005526 ·Status: COMPLETED
-
Aortic Dilatation Under 5 cm: Genetic Risk Mapping
NCT07034430 ·Status: ACTIVE_NOT_RECRUITING
-
Genetic Profile in Patients With Aortic Syndrome
NCT04751058 ·Status: COMPLETED
-
Genetics of Aortic Stenosis: From Family Forms to the Common Forms
NCT02890407 ·Status: COMPLETED
-
Is There a Genetic Predisposition for Acute Stress-induced (Takotsubo) Cardiomyopathy
NCT04513054 ·Status: RECRUITING ·Phase: NA
-
Genetic Investigations in Spontaneous Coronary Artery Dissection (SCAD)
NCT01427179 ·Status: RECRUITING
-
A Study to Evaluate the Feasibility of Screening Relatives of Patients Affected by Non-Syndromic Thoracic Aortic Diseases
NCT03861741 ·Status: UNKNOWN ·Phase: NA
-
Genetic of Aortic Valve Stenosis - Clinical and Therapeutic Implications
NCT00647088 ·Status: UNKNOWN
-
Risk Factors of Individuals With Coronary Artery Disease
NCT00260104 ·Status: UNKNOWN
-
Genetic Determinants of Sudden Cardiac Death
NCT00064558 ·Status: COMPLETED
-
Molecular Studies on Hereditary Haemorrhagic Telangiectasia Families
NCT00230620 ·Status: RECRUITING
-
National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions
NCT01322165 ·Status: COMPLETED
-
Molecular Autopsy Study
NCT02168088 ·Status: RECRUITING
-
Risk and Resilience in Pulmonary Arterial Hypertension and Genetically Susceptible Individuals
NCT05584722 ·Status: RECRUITING
-
A Study to Identify Differences in Gene Expression in Patients With Bicuspid and Tricuspid Valve Disease
NCT01194362 ·Status: COMPLETED
-
Genomics of Sudden Cardiac Arrest
NCT00661128 ·Status: ACTIVE_NOT_RECRUITING
-
Cardiac AResT And GENEtic
NCT00604149 ·Status: COMPLETED
-
Genetic- and Biological-Markers of Predisposition to Atherosclerosis: Leipzig-Heart Study
NCT00497887 ·Status: UNKNOWN
-
Genetic and Epidemiologic Studies of Premature Coronary Artery Disease - SCOR in Arteriosclerosis
NCT00005324 ·Status: COMPLETED
-
Identification of Genetic Markers Modulating Rhythmic Risk Among Patients With Severe Cardiomyopathy
NCT02852018 ·Status: COMPLETED
-
Genetic Architecture of Plasma T-PA and PAI-1
NCT00007410 ·Status: COMPLETED
-
Stratification of Arrhythmic Risk and/or Heart Failure Risk in Patients With Hereditary Heart Disease
NCT07257289 ·Status: RECRUITING
-
Genetic Architecture of Heart Disease in Rural Brazil
NCT00023556 ·Status: COMPLETED
-
Genetic Characterization of Patients With Arrhythmia-Induced Cardiomyopathy
NCT06896266 ·Status: RECRUITING
-
Vascular Disease Discovery Protocol
NCT03538639 ·Status: RECRUITING