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Maintaining Mechanisms of Chronic Depression and Their Changeability

NCT02801513 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 74

Last updated 2016-06-16

No results posted yet for this study

Summary

Despite considerable progress in the understanding of depression, the treatment of those who have entered a chronic course of the disorder still represents a major challenge. In order to develop more effective interventions it is important to learn more about maintaining mechanisms and the ways in which these can be addressed. Recent research has outlined aberrations in neurophysiological parameters that may serve as risk factors underlying tendencies to engage in maladaptive responses to negative mood, and that may be particularly pronounced in patients with chronic depression. Initial evidence suggests that such deficits may not be easily amenable through established treatments. The current study investigated whether mental training using mindfulness mediation, as compared to an active control training, could alter these parameters in chronically depressed patients.

Conditions

Interventions

BEHAVIORAL

Brief Mindfulness Training

Brief mindfulness training comprising of three weekly individual sessions and daily guided meditation home practice

BEHAVIORAL

Resting Control Training

Brief resting control training comprising of three weekly individual sessions and daily home practice consisting of resting periods

Sponsors & Collaborators

  • Charite University, Berlin, Germany

    collaborator OTHER

  • Freie Universität Berlin

    lead OTHER

Principal Investigators

  • Thorsten Barnhofer, PhD · Freie Universität Berlin

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-09-30
Primary Completion
2015-03-31
Completion
2015-03-31

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02801513 on ClinicalTrials.gov