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Etomidate to Improve Outcome in Elderly Patients

NCT02910206 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 1917

Last updated 2020-12-10

No results posted yet for this study

Summary

Elderly patients have high mortality and postoperative complications rate after surgery, especially postoperative cardiac complications. A meta-analysis revealed haemodynamic intraoperative events significantly increased the risk of postoperative cardiac complications.To limit the risk, optimize the intraoperative management of circulation is essential. Anesthetic drug may effect on the haemodynamic intraoperative, reduction of postoperative complications should aimed at choosing the optimal anesthetic drug with minimal effect on haemodynamic.So this study is to explore the comparative efficacy and safety of anesthetic drug (etomidate or propofol) in elderly patients

Conditions

  • Postoperative Complications

Interventions

DRUG

Etomidate

etomidate is given intravenously

DRUG

propofol

propofol is given intravenously

DRUG

Sufentanil

sufentanil is given intravenously

DRUG

Cisatracurium

Cisatracurium is given intravenously

Sponsors & Collaborators

  • Zhihong LU

    lead OTHER

Principal Investigators

  • Lize Xiong, PhD · Xijing hosptial

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
65 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-08-15
Primary Completion
2019-11-20
Completion
2020-11-20

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02910206 on ClinicalTrials.gov