Predictors of Suicidal Behavior in Depression

Summary

This study aims at identifying predictors of suicidal behaviors in depressed subjects. Investigators will first compare demographic, clinical, and biological features of depressed recent suicide attempters (within one week) and depressed subjects without lifetime history of suicide attempt. Baseline risk factors for suicide will be used to predict the risk of attempting suicide during a one year follow-up. A thorough evaluation of these patients will allow to identify the factors associated with suicidal risk and develop a simplified risk score that could be used in clinical settings to improve our practice.

Conditions

• Suicidal Behavior
• Depression
• Traumatic Events
• Impulsivity Aggression

Interventions

OTHER

Standardized assessment on depressed patients

At inclusion, socio-demographic characteristics, main life events, psychopathology (comorbidity, personality dimensions, characterisation of SB) and biological sample will be performed by psychiatrist and nurse. Investigators will retrieve the results of biological assays routinely made as part of standard collect biological results routinely done for all depressed patient. At follow-up (3 months, 6 months, 12 months), they will assess thymic state, occurrence of suicidal ideation and suicide attempt and environmental stressors. In case of non response, the general physician or the psychiatrist in charge of the patient will be contacted to assess the occurrence of SB during the year. In case of death or absence of clinical information, a request for cause of death certificate will be carried out through tne National Institute of Health and Medical research (INSERM) Unit 1018 / Epidemiological center on medical causes of death (CépiDc).

Sponsors & Collaborators

• University Hospital, Lille

  collaborator OTHER

• Centre Hospitalier Universiatire La Conception, Marseille

  collaborator UNKNOWN

• Centre Hospitalier Régional et Universitaire de Brest

  collaborator OTHER

• Hôpital Saint Anne, Paris

  collaborator UNKNOWN

• Créteil Hospital

  collaborator OTHER

• Centre Hospitalier Charles Perrens, Bordeaux

  collaborator OTHER_GOV

• Centre Hospitalier Universiatire Lyon

  collaborator UNKNOWN

• Centre Hospitalier Universitaire de Nīmes

  collaborator OTHER

• INSERM U1061 Montpellier

  collaborator UNKNOWN

• Centre Hospitalier Universitaire de Besancon

  collaborator OTHER

• University Hospital, Montpellier

  lead OTHER

Study Design

Allocation

NA

Purpose

SCREENING

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2015-03-31

Primary Completion

2018-03-31

Completion

2018-03-31

Countries

• France

Study Locations