Fluorine F 18 Fluorodopa-Labeled PET Scan in Planning Surgery and Radiation Therapy in Treating Patients With Newly Diagnosed High- or Low-Grade Malignant Glioma

Summary

RATIONALE: New imaging procedures, such as fluorine F 18 fluorodopa-labeled PET scan, may help in guiding surgery and radiation therapy and allow doctors to plan better treatment.

PURPOSE: This clinical trial studies fluorine F 18 fluorodopa-labeled PET scan in planning surgery and radiation therapy in treating patients with newly diagnosed high- or low-grade malignant glioma

Conditions

• Adult Anaplastic Astrocytoma
• Adult Anaplastic Ependymoma
• Adult Anaplastic Oligodendroglioma
• Adult Brain Stem Glioma
• Adult Diffuse Astrocytoma
• Adult Ependymoma
• Adult Giant Cell Glioblastoma
• Adult Glioblastoma
• Adult Gliosarcoma
• Adult Mixed Glioma
• Adult Myxopapillary Ependymoma
• Adult Oligodendroglioma
• Adult Pilocytic Astrocytoma
• Adult Pineal Gland Astrocytoma
• Adult Subependymal Giant Cell Astrocytoma
• Adult Subependymoma

Interventions

PROCEDURE

biopsy

Correlative studies

PROCEDURE

computed tomography

Undergo computed tomography

PROCEDURE

therapeutic conventional surgery

Undergo stereotactic craniotomy

RADIATION

radiation therapy treatment planning/simulation

Undergo radiation therapy treatment planning/simulation

RADIATION

radiation therapy

Undergo radiation therapy

PROCEDURE

magnetic resonance imaging

Undergo magnetic resonance imaging

PROCEDURE

positron emission tomography

Undergo positron emission tomography

DRUG

fluorine F 18 fluorodopa

Given IV

Sponsors & Collaborators

• Mayo Clinic

  lead OTHER

Principal Investigators

• Nadia N. Laack, M.D. · Mayo Clinic

Study Design

Allocation

NA

Purpose

DIAGNOSTIC

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2010-07-26

Primary Completion

2013-11-05

Completion

2019-07-26

Countries

• United States

Study Locations