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PET Imaging of High-grade Glioma Using 18F-fluoromethylcholine: a Tool for the Early Detection of Tumour Recurrence After Combined Radiochemotherapy?

NCT00628940 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2018-05-18

No results posted yet for this study

Summary

The aim of the study is to define preferential sites of tumour recurrence by observing tracer uptake in the tumour in sequential PET images with 18F-fluoromethylcholine (and perfusion MR, see also below). Changes in the intensity of the tracer uptake in the tumour during and after the course of radiotherapy will be correlated with the site of tumour recurrence as will be assessed by conventional MRI. In due time, these results must enable clinicians to change their therapeutic approach of high-grade glioma.

Conditions

  • High-grade Glioma of the Brain

Interventions

RADIATION

PET images with 18F-fluoromethylcholine

sequential PET images with 18F-fluoromethylcholine

Sponsors & Collaborators

  • Research Foundation Flanders

    collaborator OTHER

  • Special Research Fund, Belgium

    collaborator UNKNOWN

  • University Ghent

    lead OTHER

Principal Investigators

  • Ingeborg Goethals, MD, PhD · University Hospital, Ghent

Study Design

Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-01-12
Primary Completion
2017-03-14
Completion
2018-03-22

Countries

  • Belgium

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00628940 on ClinicalTrials.gov