Cross-over Double-blind Intervention to Investigate the Effects of Defined Antioxidant-containing Drinks on Time Course of Antioxidant Capacity
NCT02898571 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10
Last updated 2016-09-13
Summary
The aim of this project is to measure the differences in antioxidant capacity at different time points after consuming a single dose of antioxidant-containing drink (vitamin C or epicatechin) compared with a control drink in 10 volunteers, and then match the data with the proposed modelling corresponding to either homeostasis or accumulation. Additionally it will also determine whether the effect on changes of antioxidant capacity in response to epicatechin and vitamin c is equal.
Conditions
- The Impact of Vitamin c and Epicatechin Upon Antioxidant Capactity
Interventions
- DIETARY_SUPPLEMENT
-
Placebo
Placebo comparitor
- DIETARY_SUPPLEMENT
-
Vitamin C
Active treatment
- DIETARY_SUPPLEMENT
-
epicatechin
Active treatment
Sponsors & Collaborators
-
Linkoeping University
collaborator OTHER_GOV -
Newcastle University
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- TRIPLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 35 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2016-07-31
- Primary Completion
- 2017-01-31
Countries
- United Kingdom
Study Locations
More Related Trials
-
Effect of Polyphenol Extract on Cardiovascular Health Markers: a 4 Way Randomised Crossover Study
NCT05220059 ·Status: UNKNOWN ·Phase: NA
-
Bioavailability of Carotenoids and Flavonoids From Fresh Oranges and Orange Juice.
NCT02380144 ·Status: UNKNOWN ·Phase: NA
-
Dietary Polyphenols and Insulin Sensitivity in Overweight and Obese Humans
NCT02381145 ·Status: COMPLETED ·Phase: NA
-
Effect of Grape Seed Extract Plus Ascorbic Acid on Endothelial Function
NCT00554242 ·Status: COMPLETED ·Phase: NA
-
Antioxidant Supplementation in Pregnant Women With Low Antioxidant Status
NCT00388856 ·Status: COMPLETED ·Phase: PHASE2
-
Effects of Dietary Ingredients on Vascular Function
NCT02158481 ·Status: COMPLETED ·Phase: NA
-
Effects of Anthocyanin on Skin Health and Markers of Cardiovascular Disease Risk
NCT00574574 ·Status: COMPLETED ·Phase: NA
-
Vitamin C to Reduce Morning Cardiovascular Risk
NCT03290612 ·Status: COMPLETED ·Phase: NA
-
Chronic Resveratrol Supplementation in Healthy Humans
NCT01640197 ·Status: COMPLETED ·Phase: PHASE1
-
Dietary Antioxidants, Redox Tone and Health Promotion: an Orthomolecular Study of Interactions
NCT01315977 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Effects of Oral Antioxidant Cocktail in Cardiovascular Disease Patients
NCT03629613 ·Status: WITHDRAWN ·Phase: NA
-
The Effect of Fruit and Fruit Juice on Plasma Total Antioxidant Capacity
NCT00545415 ·Status: COMPLETED ·Phase: NA
-
The Bioavailability of Polyacetylenes From Carrots Study
NCT02696473 ·Status: COMPLETED ·Phase: NA
-
A Study of Biological Effects of a Polyphenol Supplement
NCT05829382 ·Status: COMPLETED ·Phase: NA
-
Bioavailability of Flavonoids and Phenolic Acids From Cranberry Juice Cocktail in Healthy Older Adults
NCT00740077 ·Status: COMPLETED ·Phase: NA
-
Absorption, Metabolism and Excretion of Dietary Polyphenolic Bioactives in Humans
NCT03194620 ·Status: COMPLETED ·Phase: NA
-
Absorption and Antioxidant Effects of Polyphenolics From Acai
NCT02227628 ·Status: COMPLETED ·Phase: NA
-
The Effect of Citrus Extract on Oxidative Stress
NCT03580447 ·Status: COMPLETED ·Phase: NA
-
Plasma-Induced Changes in the Metabolome Following Polyphenol Consumption
NCT06144489 ·Status: COMPLETED ·Phase: NA
-
Bioavailability Study of Different Dietary Antioxidants in Volunteers
NCT01199549 ·Status: COMPLETED
-
Assessment of Short-term Effect of L-Citrulline on Endothelial Function and Vasodilation in Known CAD Patients
NCT02638727 ·Status: UNKNOWN ·Phase: NA
-
Polyphenols and Endothelial Function
NCT00619749 ·Status: TERMINATED ·Phase: PHASE3
-
In Vitro and in Vivo Evaluation of the Anti-Inflammatory and Antithrombotic Synergy of Vitamin C and Bioflavonoids in Healthy Subjects
NCT07061431 ·Status: COMPLETED ·Phase: NA
-
The Juice Study: Sensitivity of Skin Carotenoid Status to Detect Change in Intake
NCT03202043 ·Status: COMPLETED ·Phase: NA
-
The Effects of a Polyphenol-enriched Fruit Drink on Metabolic Health
NCT01706653 ·Status: COMPLETED ·Phase: NA