MedTrace Logo

The Effect of Correction of Metabolic Acidosis in CKD on Intrarenal RAS Activity

NCT02896309 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 45

Last updated 2019-06-20

No results posted yet for this study

Summary

This study evaluates the effect of oral sodium bicarbonate treatment on the intrarenal renin-angiotensin-system in adult patients with a metabolic acidosis and chronic kidney disease. This treatment is compared to sodium chloride treatment, which serves as control for increased sodium-intake and no treatment, which serves as time-control.

Conditions

Interventions

DIETARY_SUPPLEMENT

Sodium bicarbonate

DIETARY_SUPPLEMENT

Sodium chloride

Sponsors & Collaborators

Principal Investigators

  • Ewout J Hoorn, MD, PhD · Erasmus Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
100 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-09-30
Primary Completion
2018-12-27
Completion
2018-12-27

Countries

  • Netherlands

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02896309 on ClinicalTrials.gov